I set up the game against Illiria as a huge world without pod scattering and chose Morgan. The AI's in that one are the Angels, the Spartan Federation, the CyC, the Pirates, and the Caretakers.
I set up the game against stuntman19 as a huge world with pod scattering and chose the Gaians
. The AI factions are the Angels, the CyC, the University, the Drones, and the Caretakers.
A couple of things I noticed in a test: in MP, the Progenitors land in MY 2101 (whereas in SP they land in 2105), and their ability for directed research seems to be buggy: it seems they get blind research like anyone else if the multiplayer game is set that way. Which helps play balance but isn't what I was expecting...